​

• Improved 6- year overall survival in AT/RT –results of the registry study Rhabdoid 2007 (Bartelheim, Nemes, et al)

• ATRTs are composed of three epigenetic subgroups... suggest potential therapeutic targets (Johann et al)

• Roberts Lab Update, April 10, 2015

• Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis (Torchia et al)

• Pitfalls in the diagnosis of atypical teratoid rhabdoid (AT/RT): experiences from the European rhabdoid tumor registry (Hasselblatt, Kordes, et al)

• Integrated genomics has identified a new AT/RT-like yet INI1-positive brain tumor subtype among primary pediatric embryonal tumors (Ho, Shih, Liang et al)

• Atypical teratoid rhabdoid tumor: improved long-term survival with an intensive multimodal therapy and delayed radiotherapy. (Slavc, Chocholous et al)

• Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2 (Knutson, Warholic, et al) 

• Atypical Teratoid Rhabdoid Tumors (Venneti, Kalpana et al)

• Molecular Pathways: SWI/SNF (BAF) Complexes Are Frequently Mutated in Cancer—Mechanisms and Potential Therapeutic Insights (Wang, Haswell & Roberts)

• Pediatric Brain Cancer Research (Dana Farber Cancer Institute)

• Atypical Teratoid Rhabdoid Tumours (AT/RT): A French Retrospective Study

• Atypical Teratoid Rhabdoid Tumors (Sredni & Lulla)

• Rhabdoid tumors: integrating biological insights with clinical success (Bourdeaut, Chi, Fruwald)

• Atypical Teratoid Rhabdoid Tumors: Current Therapy and Future Directions (Ginn & Gajjar)

• Survival outcomes in atypical teratoid rhabdoid tumor for patients undergoing radiotherapy in a Surveillance, Epidemiology, and End Results analysis (Buscariollo, Park et al)

• Atypical teratoid rhabdoid tumor: long-term survival after chemoradiotherapy (Verma & Johnson)

• Targeting Aurora Kinase A enhances radiation sensitivity of atypical teratoid rhabdoid tumor cells (Venkataraman, Alimova et al)

• Vulnerabilities of Mutant SWI/SNF Complexes in Cancer (Helming, Wang & Roberts)

 

 

Hospitals

 

• Boston Childrens Hospital

• Dana Farber Cancer Institute

• St Judes Childrens Research Hospital

• iSTAR AT/RT Laborator, Childrens Hospital Chicago